Description

Mice lacking the function of the PcG protein CBX2 (also known as M33) show defects in gonadal, adrenal, and splenic development. In particular, XY knockout mice develop ovaries but not testes, and the gonads are hypoplastic in both sexes.

Publication Title

Cbx2, a polycomb group gene, is required for Sry gene expression in mice.

Alternate Accession IDs

E-GEOD-29485

Sample Metadata Fields

Specimen part