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accession-icon GSE10970
Efficient Array-based Identification of Novel Cardiac Genes through Differentiation of Mouse ESCs
  • organism-icon Mus musculus
  • sample-icon 12 Downloadable Samples
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Description

Cardiac disease accounts for the largest proportion of adult mortality and morbidity in the industrialized world. However, progress toward improved clinical treatments is hampered by an incomplete understanding of the genetic programs controlling early cardiogenesis. To better understand this process, we set out to identify genes whose expression is enriched within early cardiac fated populations, obtaining the transcriptional signatures of mouse embryonic stem cells (mESCs) differentiating along a cardiac path.

Publication Title

Efficient array-based identification of novel cardiac genes through differentiation of mouse ESCs.

Alternate Accession IDs

E-GEOD-10970

Sample Metadata Fields

No sample metadata fields

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accession-icon GSE45229
Unique pharmacological actions of atypical neuroleptic quetiapine: possible role in cell cycle/fate control
  • organism-icon Mus musculus
  • sample-icon 20 Downloadable Samples
  • Technology Badge Icon

Description

Quetiapine is an atypical neuroleptic with a pharmacological profile distinct from classic neuroleptics. It is currently approved for treating patients with schizophrenia, major depression and bipolar I disorder. However, its cellular effects remain elusive.

Publication Title

Unique pharmacological actions of atypical neuroleptic quetiapine: possible role in cell cycle/fate control.

Alternate Accession IDs

E-GEOD-45229

Sample Metadata Fields

Sex, Treatment

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refine.bio is a repository of uniformly processed and normalized, ready-to-use transcriptome data from publicly available sources. refine.bio is a project of the Childhood Cancer Data Lab (CCDL)

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Cite refine.bio

Casey S. Greene, Dongbo Hu, Richard W. W. Jones, Stephanie Liu, David S. Mejia, Rob Patro, Stephen R. Piccolo, Ariel Rodriguez Romero, Hirak Sarkar, Candace L. Savonen, Jaclyn N. Taroni, William E. Vauclain, Deepashree Venkatesh Prasad, Kurt G. Wheeler. refine.bio: a resource of uniformly processed publicly available gene expression datasets.
URL: https://www.refine.bio

Note that the contributor list is in alphabetical order as we prepare a manuscript for submission.

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